What are Baby Blues and Postpartum Depression and how are they different? Baby Blues are very common after childbirth. They happen during the first two weeks after giving birth. It is usually just your adjustment period to your new way of life. Baby Blues will go away on its own and doesn't require help from a doctor. Postpartum Depression is when you have symptoms of feeling depressed, anxious, OCD, and sometimes even psychosis. These feelings continue after the first two we